Dublin Core
Title
Saliva and Oral Diseases
Subject
dental health
Description
Saliva is a fascinating biological fluid which has all the features of a perfect diagnostic tool.
In fact, its collection is rapid, simple, and noninvasive. Thanks to several transport mechanisms
and its intimate contact with crevicular fluid, saliva contains hundreds of proteins deriving from
plasma. Advances in analytical techniques have opened a new era—called “salivaomics”—that
investigates the salivary proteome, transcriptome, microRNAs, metabolome, and microbiome.
In recent years, researchers have tried to find salivary biomarkers for oral and systemic diseases
with various protocols and technologies. The review aspires to provide an overall perspective of
salivary biomarkers concerning oral diseases such as lichen planus, oral cancer, blistering diseases,
and psoriasis. Saliva has proved to be a promising substrate for the early detection of oral diseases
and the evaluation of therapeutic response. However, the wide variation in sampling, processing,
and measuring of salivary elements still represents a limit for the application in clinical practice.
In fact, its collection is rapid, simple, and noninvasive. Thanks to several transport mechanisms
and its intimate contact with crevicular fluid, saliva contains hundreds of proteins deriving from
plasma. Advances in analytical techniques have opened a new era—called “salivaomics”—that
investigates the salivary proteome, transcriptome, microRNAs, metabolome, and microbiome.
In recent years, researchers have tried to find salivary biomarkers for oral and systemic diseases
with various protocols and technologies. The review aspires to provide an overall perspective of
salivary biomarkers concerning oral diseases such as lichen planus, oral cancer, blistering diseases,
and psoriasis. Saliva has proved to be a promising substrate for the early detection of oral diseases
and the evaluation of therapeutic response. However, the wide variation in sampling, processing,
and measuring of salivary elements still represents a limit for the application in clinical practice.
Creator
Pia Lopez-Jornet (Ed.)
Source
https://www.mdpi.com/books/pdfview/book/3833
Publisher
MDPI - Multidisciplinary Digital Publishing Institute
Date
June 2021
Contributor
Dwi Prihastuti
Rights
https://creativecommons.org/licenses/by/4.0/
Format
Pdf
Language
English
Type
Textbooks
Identifier
https://doi.org/10.3390/books978-3-0365-0777-4