Dublin Core
Title
Spumaretroviruses
Subject
virus zoonosis
Description
Foamy viruses, currently referred to as spumaretroviruses, are the most ancient retroviruses as evidenced by traces of viral sequences dispersed in all vertebrate classes from fish to mammals. Additionally, infectious foamy viruses circulate in a variety of mammalian species including simian, bovine, equine, caprine, and feline. Foamy viruses have many unique features which led to the division of the retrovirus family into two subfamilies, the Orthoretrovirinae and Spumaretrovirinae. In vitro, foamy viruses have a broad host range and in vivo, human infections have been described due to cross-species transmission from infected nonhuman primates. Thus far, there are no reports of virus-induced disease in humans or in the natural host species. These unique properties of foamy viruses have led researchers to develop foamy viruses as gene therapy vectors to study virus–virus and virus–host interactions for identifying factors involved in virus replication, transmission, and immune regulation that could influence potential clinical outcomes in humans as well as for using endogenous foamy virus sequences in the analysis of host species evolution.
Creator
Khan, Arifa (editor)
Löchelt, Martin (editor)
Lindemann, Dirk (editor)
Löchelt, Martin (editor)
Lindemann, Dirk (editor)
Source
https://directory.doabooks.org/handle/20.500.12854/76747
Publisher
MDPI - Multidisciplinary Digital Publishing Institute
Date
2021
Contributor
Sulistiorini
Rights
https://creativecommons.org/licenses/by/4.0/
Relation
1. Ottmar Herchenr¨oder, Martin L¨ochelt, Florence Buseyne, Antoine Gessain,
Marcelo A. Soares, Arifa S. Khan and Dirk Lindemann
Twelfth International Foamy Virus Conference—Meeting Report
Reprinted from: Viruses 2019, 11, 134, doi:10.3390/v11020134
2. Andre´ F. Santos, Liliane T. F. Cavalcante, Cl´audia P. Muniz, William M. Switzer
and Marcelo A. Soares
Simian Foamy Viruses in Central and South America: A New World of Discovery
Reprinted from: Viruses 2019, 11, 967, doi:10.3390/v11100967
3. Sandra M. Fuentes, Eunhae H. Bae, Subhiksha Nandakumar, Dhanya K. Williams
and Arifa S. Khan
Genome Analysis and Replication Studies of the African Green Monkey Simian Foamy Virus
Serotype 3 Strain FV2014
Reprinted from: Viruses 2020, 12, 403, doi:10.3390/v12040403
Marcelo A. Soares, Arifa S. Khan and Dirk Lindemann
Twelfth International Foamy Virus Conference—Meeting Report
Reprinted from: Viruses 2019, 11, 134, doi:10.3390/v11020134
2. Andre´ F. Santos, Liliane T. F. Cavalcante, Cl´audia P. Muniz, William M. Switzer
and Marcelo A. Soares
Simian Foamy Viruses in Central and South America: A New World of Discovery
Reprinted from: Viruses 2019, 11, 967, doi:10.3390/v11100967
3. Sandra M. Fuentes, Eunhae H. Bae, Subhiksha Nandakumar, Dhanya K. Williams
and Arifa S. Khan
Genome Analysis and Replication Studies of the African Green Monkey Simian Foamy Virus
Serotype 3 Strain FV2014
Reprinted from: Viruses 2020, 12, 403, doi:10.3390/v12040403
Format
pdf
Language
English
Type
Textbooks
Identifier
DOI: 10.3390/books978-3-0365-0595-4