Biomarkers in drug hypersensitivity

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Dublin Core

Title

Biomarkers in drug hypersensitivity

Subject

drug hypersensitivity

Description

Drug-induced hypersensitivity reactions play a prominent role among adverse drug effects, and constitute a major health problem. It has been suggested that up to 6% of all hospital admissions are related to these reactions. Biomarkers, especially those based on pharmacogenomics testing, have proved to be extremely useful for type A adverse drug reactions. Clinical practice guidelines based on biomarker testing are presently being developed and updated for type A adverse drug reactions. In contrast, little attention has been paid to the potential use of biomarkers in type B adverse reactions, characterized by the occurrence of reactions not directly related to the pharmacological properties of the drug. Drug-induced hypersensitivity belongs to those type B reactions.

Creator

Jose A. G. Agundez , et al

Source

https://www.frontiersin.org/research-topics/4326/biomarkers-in-drug-hypersensitivity

Publisher

Frontiers Media SA

Date

2017

Contributor

Tatik

Rights

Creative Commons

Format

PDF

Language

English

Type

Textbooks

Identifier

ISSN 1664-8714
ISBN 978-2-88945-226-2
DOI 10.3389/978-2-88945-226-2

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