Stem Cell Research in Cardiology

Stem Cell Research in Cardiology

cardiology

Even today, cardiovascular disease is the leading cause of death worldwide, and therapeutic approaches remain very limited. Due to the limited regenerative ability of late-differentiated cardiomyocytes post-injury, new strategies for treating cardiac patients are urgently needed. Post myocardial injury, resident fibroblasts begin to produce extracellular matrix, resulting in fibrosis and ultimately heart failure. Recently, preclinical investigations and clinical trials have raised hopes for stem cell-based approaches, as effective therapeutic options for these diseases.So far, several types of stem cells have been identified as promising candidates for use in medicine: cardiac progenitor cells, bone marrow-derived stem cells, embryonic and induced pluripotent stem cells, and their progeny. Moreover, innovative techniques of direct heart cell reprogramming offer promising options for cardiovascular research, in vitro and in vivo. Therefore, investigation of the underlying and associated mechanisms that trigger the therapeutic effects of stem cell application becomes crucial to improve the approach to cardiac patients. This Special Issue of Cell provides the latest developments in the rapidly growing field of regenerative medicine in cardiology.

David, Robert (editors)

https://directory.doabooks.org/handle/20.500.12854/69152

MDPI - Multidisciplinary Digital Publishing Institute

2020

Dewi Puspitasari

https://creativecommons.org/licenses/by/4.0/

https://mdpi.com/books/pdfview/book/2924

Pdf

English

Textbooks

DOI
10.3390/buku978-3-03943-193-9

ISBN
9783039431922, 9783039431939

Basel