mTOR Signaling in Metabolism and Cancer

mTOR Signaling in Metabolism and Cancer

Cancer

The mechanistic/mammalian target of rapamycin (mTOR), a serine/threonine kinase, is a central regulator for human physiological activity. Deregulated mTOR signaling is implicated in a variety of disorders, such as cancer, obesity, diabetes, and neurodegenerative diseases. The papers published in this Special Issue summarize the current understanding of the mTOR pathway and its role in the regulation of tissue regeneration, regulatory T cell differentiation and function, and different types of cancer including hematologic malignancies, skin, prostate, breast, and head and neck cancer. The findings highlight that targeting mTOR pathway is a promising strategy to fight against certain human diseases.

Huang, Shile (editor)

https://directory.doabooks.org/handle/20.500.12854/69370

MDPI - Multidisciplinary Digital Publishing Institute

2020

Dewi Puspitasari

https://creativecommons.org/licenses/by/4.0/

Liu, G.Y.; Sabatini, D.M. mTOR at the nexus of nutrition, growth, ageing and disease. Nat. Rev. Mol. Cell Biol.
2020, 21, 183–203. [PubMed]

Pdf

English

Textbooks

DOI
10.3390/books978-3-03943-554-8

ISBN
9783039435531, 9783039435548

Basel