Self-Organizing Nanovectors for Drug Delivery

Self-Organizing Nanovectors for Drug Delivery

Pharmaceutics
Pharmacy

Nanomedicine is probably one of the most investigated areas in the field of pharmaceutics in the last two decades. Nanotechnology-based formulations have been mainly investigated as a useful tool for drug delivery and targeting. Despite the wide literature on this subject and the growing number of formulations on the market or in clinical trials, the success rate of nanomedicines from bench to bedside is still low. Among the proposed approaches to facilitate the technology transfer of nanomedicines, biomaterials, and formulations able to spontaneously form nanoscale systems are very attractive. In this context, lipids and polymers have been proposed for the delivery of nucleic acids; polypeptides have been studied as building materials for drug delivery systems; inorganic or polymeric biomaterials have been combined to assemble in hybrid nanosystems, by mixing two or more components or by layer-by-layer strategy. Finally, formulations able to self-emulsify have been proposed, especially for oral administration. All these approaches do not require high energy for the preparation and should be easy to transfer to large scale production with limited costs of production. The growing attention toward self-organizing nanostructures in the field of pharmaceutics will certainly contribute to speeding up the technology transfer of nanotechnology-based formulations.

Giuseppe De Rosa (Ed.)
Pietro Matricardi (Ed.)

https://www.mdpi.com/journal/pharmaceutics/special_issues/self organizing delivery

MDPI
St.
Alban-Anlage 66
4052 Basel, Switzerland

2020

Giuseppe De Rosa
Pietro Matricardi
J®F

CC BY-NC-ND

Pdf

English

Textbooks

ISBN 978-3-03928-428-3 (Pbk)
ISBN 978-3-03928-429-0 (PDF)