This Special Issue is a collection of eleven articles (five reviews and six studies) that
describe a wide range of approaches to modulating metalloproteinase activity in
disease. The techniques described are in vitro, in vivo, and ex vivo.
In this Special Issue, recent advancements in the field of pediatric tumors are discussed,
and novel prognostic markers are critically appraised. Greater understanding of the
heterogeneity of pediatric cancers will ultimately lead to new therapeutic…
Lipid-based nanosystems, including solid lipid nanoparticles (SLN) and nanostructured
lipid carriers (NLC), cationic lipid nanoparticles, nanoemulsions, and liposomes, have
been extensively studied to improve drug delivery through different…
Cancer is one of the leading causes of morbidity and mortality in humans today, and the number of people affected by cancer is growing. As a result, the search for new antitumor agents that may be more effective and secure than existing treatments is…
The healthcare system’s ability to diagnose and care for people with schizophrenia has
improved in recent decades, as effective pharmacological and psychosocial interventions
are now available. However, schizophrenia remains a leading cause of…
Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimizing biological treatment in patients with inflammatory bowel disease (IBD) and other immune- mediated inflammatory diseases (IMID). Reactive TDM has rationalized the management…
Steroids are a large group of compounds whose structure is based on a 17-carbon
skeleton, with a specific cyclopentanoperhydrophenanthrene ring system. Natural
steroids have been fine-tuned through evolution to build membranes; act as…
Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and
remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory
disorders of complex etiology, posing clinical challenges due to their o6en…
This book offers exciting and often surprising insights into one hundred diseases that have emerged over the past century. The authors focus on the period from 1923, when Radboud University was founded, to 2023, the university's centennial…
Exploring a wide variety of visualizations of pregnancy and fetuses through 300 years of history, this timely volume offers a fresh look at the influential feminist concept of the "public fetus." Images of pregnant and fetal bodies are today visible…