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Paris Climate Agreement: Beacon of Hope
Climate Change; Climate Change Management and Policy; Energy Economics
Quantization on Nilpotent Lie Groups
Topological Groups, Lie Groups; Abstract Harmonic Analysis; Functional Analysis; Mathematical Physics
Agricultural Implications of the Fukushima Nuclear Accident
Artificial Intelligence (incl. Robotics); Data Mining and Knowledge Discovery; Information Systems Applications (incl. Internet); User Interfaces and Human Computer Interaction; Pattern Recognition; Computer Communication Networks
Chapter Challenges and New Frontiers in the Paediatric Drug Discovery and Development
Drug discovery and development advances in the last decades allowed to find a treatment for many preventable diseases. However, all too often, children are excluded from these progresses since most of the new medicines have been discovered and…
Chapter Bioreactor-Based Bone Tissue Engineering
Omega-3 (ω-3) and omega-6 (ω-6) are polyunsaturated fatty acids (PUFAs) that play critical role in human health and have to be provided by food. In the brain, PUFAs are also precursors of endocannabinoids. The aim of this chapter is to review the…
Chapter Assessing the Performance of Personal Protective Equipment1
Schistosomiasis is the second most prevalent parasitic disease in the world. Currently, the treatment of this disease relies on a single drug, praziquantel, and due to the identification of resistant parasites, the development of new drugs is urged.…
Chapter 7 Vitamin C in Pneumonia and Sepsis
In humans, ascorbic acid is an essential vitamin, anti-oxidant and co-factor of a variety of metal ion-dependent enzymatic reactions. In this review, the transport of L-ascorbic acid is described from food to target cells. Transport of ascorbic acid…
Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target
In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable diverse, pharmacophoric rich,…