Dublin Core
Title
Marine Compounds and Cancer
Subject
Cancer
Description
In Western countries, cancer is among the most frequent causes of death. Despite striking advances in cancer therapy, especially by the so called “targeted agents”, there is still an urgent need for new drugs in oncology. Hope comes from the marine environment, which is a rich source of natural compounds showing anti-cancer activity. To date, four marine cytotoxic substances, namely cytarabine, trabectidine, eribulin, and monomethyl auristatin E (as a drug-antibody conjugate named vedotin) have made it into clinical routine. Many more are in all phases of clinical testing, and a plethora of substances has already been examined for in vitro and in vivo activity.
Creator
Friedemann Honecker (Ed.)
Source
https://www.mdpi.com/1660-3397/18/1/20
Publisher
MDPI - Multidisciplinary Digital Publishing Institute
Date
2018
Contributor
Dewi Puspitasari
Rights
http://creativecommons.org/licenses/by-nc-nd/4.0/
Relation
Skropeta, D. Deep-sea natural products. Nat. Prod. Rep. 2008, 25, 1131–1166. [CrossRef] [PubMed]
Format
Pdf
Language
English
Type
Textbooks
Identifier
https://doi.org/10.3390/md18010020
Coverage
Basel