Dublin Core
Title
Application of medical imaging
methods and artificial
intelligence in tissue engineering
and organ-on-a-chi
methods and artificial
intelligence in tissue engineering
and organ-on-a-chi
Subject
Artificial Intelligence Engineering
Description
Organ-on-a-chip (OOC) is a new type of biochip technology. Various types of
OOC systems have been developed rapidly in the past decade and found
important applications in drug screening and precision medicine. However,
due to the complexity in the structure of both the chip-body itself and the
engineered-tissue inside, the imaging and analysis of OOC have still been a big
challenge for biomedical researchers. Considering that medical imaging is
moving towards higher spatial and temporal resolution and has more
applications in tissue engineering, this paper aims to review medical imaging
methods, including CT, micro-CT, MRI, small animal MRI, and OCT, and
introduces the application of 3D printing in tissue engineering and OOC in
which medical imaging plays an important role. The achievements of medical
imaging assisted tissue engineering are reviewed, and the potential applications
of medical imaging in organoids and OOC are discussed. Moreover, artificial
intelligence - especially deep learning - has demonstrated its excellence in the
analysis of medical imaging; we will also present the application of artificial
intelligence in the image analysis of 3D tissues, especially for organoids
developed in novel OOC systems.
OOC systems have been developed rapidly in the past decade and found
important applications in drug screening and precision medicine. However,
due to the complexity in the structure of both the chip-body itself and the
engineered-tissue inside, the imaging and analysis of OOC have still been a big
challenge for biomedical researchers. Considering that medical imaging is
moving towards higher spatial and temporal resolution and has more
applications in tissue engineering, this paper aims to review medical imaging
methods, including CT, micro-CT, MRI, small animal MRI, and OCT, and
introduces the application of 3D printing in tissue engineering and OOC in
which medical imaging plays an important role. The achievements of medical
imaging assisted tissue engineering are reviewed, and the potential applications
of medical imaging in organoids and OOC are discussed. Moreover, artificial
intelligence - especially deep learning - has demonstrated its excellence in the
analysis of medical imaging; we will also present the application of artificial
intelligence in the image analysis of 3D tissues, especially for organoids
developed in novel OOC systems.
Creator
Wanying Gao 1†, Chunyan Wang 2†, Qiwei Li 1 , Xijing Zhang 3 ,
Jianmin Yuan 3 , Dianfu Li 4 *, Yu Sun 5 *, Zaozao Chen 1 * and
Zhongze Gu 1 *
Jianmin Yuan 3 , Dianfu Li 4 *, Yu Sun 5 *, Zaozao Chen 1 * and
Zhongze Gu 1 *
Publisher
Frontiers in Bioengineering and Biotechnology
Date
2022
Contributor
dwi marina
Relation
Gao et al. 10.3389/fbioe.2022.985692
Format
Pdf
Language
english
Type
Textbooks
Identifier
DOI 10.3389/fbioe.2022.985692