Dublin Core
Title
PLGA Based Drug Carrier and Pharmaceutical Applications
Subject
Drug
Drug Carrier
Pharmaceutics
Drug Carrier
Pharmaceutics
Description
Poly(lactic-co-glycolic acid) (PLGA) is one of the most successful polymers that has been used
to produce medicines, such as drug carriers (DC). This is one of the few polymers that the Food and
Drug Administration (FDA) has approved for human administration due to its biocompatibility and
biodegradability [1]. DCs produced with PLGA have gained enormous attention over recent years for
their ability to be versatile vehicles to transport different type of drugs, e.g., hydrophilic or hydrophobic
small molecules or macromolecules, and protect them from degradation and uncontrolled release [
2–6].
These drug delivery systems (DDS), including micro and nanoparticles, have the potential to modify
their surface properties and improve interactions with biological materials. Furthermore, they can also
be conjugated with specific target molecules to reach specific tissues or cells [7,8]. They are being used
for different therapeutic applications, such as vaccinations or as treatments for cancer, neurological
disorders, inflammation, and other diseases
to produce medicines, such as drug carriers (DC). This is one of the few polymers that the Food and
Drug Administration (FDA) has approved for human administration due to its biocompatibility and
biodegradability [1]. DCs produced with PLGA have gained enormous attention over recent years for
their ability to be versatile vehicles to transport different type of drugs, e.g., hydrophilic or hydrophobic
small molecules or macromolecules, and protect them from degradation and uncontrolled release [
2–6].
These drug delivery systems (DDS), including micro and nanoparticles, have the potential to modify
their surface properties and improve interactions with biological materials. Furthermore, they can also
be conjugated with specific target molecules to reach specific tissues or cells [7,8]. They are being used
for different therapeutic applications, such as vaccinations or as treatments for cancer, neurological
disorders, inflammation, and other diseases
Creator
Maria Carmo Pereira
Joana A. Loureiro
Joana A. Loureiro
Source
https://www.mdpi.com/journal/pharmaceutics/special_issues/PLGA Pharm
Publisher
MDPI
St. Alban-Anlage 66
4052 Basel, Switzerland
St. Alban-Anlage 66
4052 Basel, Switzerland
Date
2021
Contributor
Maria Carmo Pereira
Joana A. Loureiro
J®F
Joana A. Loureiro
J®F
Rights
CC BY-NC-ND.
Format
PDF
Language
English
Type
Textbooks
Identifier
ISBN 978-3-0365-0220-5 (Hbk)
ISBN 978-3-0365-0221-2 (PDF)
ISBN 978-3-0365-0221-2 (PDF)