Oral Inflammations and Systemic Diseases

Oral Inflammations and Systemic Diseases.jpg

Dublin Core

Title

Oral Inflammations and Systemic Diseases

Subject

Molecular Sciences

Description

Oralinfectionsoccurfr equentlyinhumansandoftenleadtochr onicinflammationsaf fecting
theteeth(i.e.,ascaries),thegingivaltissuessurr oundingtheteeth(i.e.,asgingivitisandendodontic
lesions),andthetooth-supportingstr uctur es(i.e.,asperiodontitis).Ithasbeenpr oposedthatthese
inflammationsar enotr estrictedtospecificsitesintheoralcavityandmayhaveanegativeimpact
onthegeneralhealthoftheaf fectedpatientsbyincr easingtheirriskofseveralwidespr eaddiseases,
suchasdiabetes,cor onaryheartdisease,peripheralarterialdisease,ischemicstr oke,andsmallvessel
diseaseinthebrain.Atleastfourbasicpathogenicmechanismsinvolvingoralinflammationin
thepathogenesisofwidespr eaddiseaseshavebeenpr oposed:(1)lowlevelbacter emiabywhich
oralbacteriaenterthebloodstr eamandinvadethebody;(2)systemicinflammationinducedby
inflammatorymediatorsr eleasedfr omthesitesoftheoralinflammationintothebloodstr eam;
(3)autoimmunitytohostpr oteinscausedbythehostimmuner esponsetospecificcomponentsof
oralpathogens;and(4)pathogenicef fectsr esultingfr omspecificbacterialtoxinspr oducedbyoral
pathogenicbacteria.
ThisSpecialIssuefocusesonseveralaspectsoftheinteractionbetweenoralinfectionsand
widespr eadsystemicdiseases.W ecollectedcontributionsintheformofr eviewsandoriginalpapers
writtenbyhighlyr eputedexpertsinthisfield.

Creator

UdoSeedorf (Ed.)
GhazalAarabi (Ed.)

Source

https://www .mdpi.com/journal/ijms/special_issues/oralijms

Publisher

MDPI
St. Alban-Anlage 66
4052 Basel, Switzerland

Date

2020

Contributor

UdoSeedorf
GhazalAarabi
J®F

Rights

CC BY-NC-ND

Format

Pdf

Language

English

Type

Textbooks

Identifier

ISBN 978-3-03936-288-2 (Hbk)
ISBN 978-3-03936-289-9 (PDF)

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