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In early March of 2020, Americans watched with uncertain terror as the novel coronavirus pandemic unfolded. One week later, Ohio announced its first confirmed cases. Just one year later, the state had over a million cases and 18,000 Ohioans had died.…

Safe drinking water, sanitation, and hygiene are crucial to human health and wellbeing. These factors are a prerequisite to health since they play a crucial role in preventing the transmission of numerous waterborne pathogens and chemical…

This open access book presents an interdisciplinary, multi-authored, edited collection of chapters on Artificial Intelligence (‘AI’) and the Law. AI technology has come to play a central role in the modern data economy. Through a combination of…

Brain diseases currently affect one in six people worldwide; they include a wide range of neurological diseases, from Alzheimer’s and Parkinson’s diseases to epilepsy, brain injuries, brain cancer, neuroinfections, and strokes. The treatment of these…

Pulmonary arterial hypertension is a severe and progressive disorder affecting the blood vessels in the lungs. Typically, symptoms first appear at around 30–40 years of age and, without treatment, can lead to fatal heart disease within a few years.…

Hernias occur when internal organs push through weak points in muscle or body tissue. There are several types of hernias, including inguinal hernias, femoral hernias, umbilical hernias and hiatus hernias. Hernias usually do not get better on their…

Breast cancer is the neoplasia with the highest incidence in the female population worldwide. Cancer originates from breast tissue, most commonly from the inner lining of milk ducts or the lobules. Histologic type, tumor grade and size, expression of…

This open access book brings conceptual clarity to the study and practice of self-determination, showing that it is, without doubt, one of the most important concepts of the international legal order. It argues that the accepted categorisation of…

Pancreatic neoplasms include different pathological entities with variable biological behavior and different treatment modalities. Surgery and adjuvant therapy are the cornerstones of the therapeutic approach; however, even after radical resection,…

metabolic diseases; obesity; type 2 diabetes; muscle glycogen; skeletal muscle microRNAs; Tryptophan-kynurenine metabolites; FNDC5/irisin; AMPK; human brown adipose tissue plasticity