Frames advance coherent interpretations of issues that suggest specific problem definitions, causes, moral evaluations, and courses of action. As such, frames highlight certain aspects of an issue, and downplay or ignore others. While the use of…
This book focuses on social transformations as one of the central topics in the social sciences. The study of European social transformations is very valuable in the context of universal discussions within social sciences: explaining invariable,…
In humans, ascorbic acid is an essential vitamin, anti-oxidant and co-factor of a variety of metal ion-dependent enzymatic reactions. In this review, the transport of L-ascorbic acid is described from food to target cells. Transport of ascorbic acid…
State-funded social protection can assist poor families in providing for disabled children, especially in the global south where most of the world’s disabled population lives. This chapter is a case study of the South African care dependency grant, a…
Adenoviruses have long been identified as good candidates for use as viral vectors in gene therapy and as vaccines. These viruses can infect multiple cell types, while in division or in quiescence, and are relatively easy to manipulate so that parts…
Schistosomiasis is the second most prevalent parasitic disease in the world. Currently, the treatment of this disease relies on a single drug, praziquantel, and due to the identification of resistant parasites, the development of new drugs is urged.…
Omega-3 (ω-3) and omega-6 (ω-6) are polyunsaturated fatty acids (PUFAs) that play critical role in human health and have to be provided by food. In the brain, PUFAs are also precursors of endocannabinoids. The aim of this chapter is to review the…
Drug discovery and development advances in the last decades allowed to find a treatment for many preventable diseases. However, all too often, children are excluded from these progresses since most of the new medicines have been discovered and…
The in vivo analysis of a model organism, such as the nematode Caenorhabditis elegans, enables fundamental biomedical studies, including development, genetics, and neurobiology. In recent years, microfluidics technology has emerged as an attractive…
Computational fluid dynamics (CFD) is the main field of computational mechanics that has historically benefited from advances in high-performance computing. High-performance computing involves several techniques to make a simulation efficient and…