This analytic study surveys the transformations of elderly care policies and practices since the early 1990s, by comparing the trajectories of two extremely different care systems: Italy, a familialistic model with no relevant changes in social…
Despite the efficiency of current cancer treatments, cancer is still a deadly disease for too many. In 2008, 7.6 million people died of cancer; with the current development, it is estimated that the annual cancer death number will grow to 13 million…
The cancer stem cell (CSC) paradigm represents one of the most prominent breakthroughs of the last decades in tumor biology. CSCs are that subpopulation within a tumor that can survive conventional therapies and as a consequence are able to fuel…
Recent years have seen the idea of a close association between nutrition and the modulation of cancer development/progression reinforced. An increasing amount of experimental and epidemiological evidence has been produced supporting the concept that…
Kidney cancer imposes a significant cancer burden and its incidence continues to rise globally. Mortality in advanced kidney cancer remains high despite oncological, surgical and multimodal optimisation. Genetic associations, heterogeneity and…
Every minute, 34 new patients are diagnosed with cancer globally. Although over the past 50 years treatments have improved and survival rates have increased dramatically for several types of cancers, many remain incurable. Several aggressive types of…
This book is a collection of in-depth chapters on many aspects of contemporary cancer treatment. Written by experts worldwide, each chapter provides a detailed summary of the state-of-the art knowledge in the area, with extensive references and clear…
This collection includes the manuscripts published in the Special Issue of Animals: Refinements toAnimal Models for Biomedical Research. Twelve peer-reviewed papers covering a range of approachesto the concept of refinement have been included in this…
This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in…