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Neuroactive chemicals are the largest group of micropollutants present in European rivers. There is increasing concern about the behavioral effects of these neuroactive chemicals on aquatic wildlife, potentially resulting in detrimental effects on…

Low back pain (LBP) is a major public health problem, being the most commonly reported musculoskeletal disorder (MSD) and the leading cause of compromised quality of life and work absenteeism. Indeed, LBP is the leading worldwide cause of years lost…

The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the…

In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable diverse, pharmacophoric rich,…

This open access book provides a snapshot of the state of contemporary access to justice in England and Wales. Legal aid lawyers provide a critical function in supporting individuals to address a range of problems. These are problems that commonly…

This open access book provides novel insights on management innovation and sustainability in motorsport. Utilizing the all-electric racing championship called Formula E as case, it draws upon data from multiple sources such as sustainability reports…

This open access book provides an overview of the building blocks necessary for managing, steering and guiding the establishment of a research infrastructure (RI). It offers valuable insights into RI investment, access and management at the academic,…

This book presents an innovative format for poetry criticism that its authors call "dialogical poetics." This approach shows that readings of poems, which in academic literary criticism often look like a product of settled knowledge, are in reality a…

Although individuals may have different goals and wishes on the surface, deep down we all want the same things. Our fundamental needs are universal: Regardless of culture, age, and lifestyle, everyone ultimately has the same set of needs. Needs are…