The Alveolar Epithelium :
Mechanisms of Injury and Repair

The Alveolar Epithelium :
Mechanisms of Injury and Repair

Epithelium

Alveolar epithelial cells (AECs) of the lung are important contributors to pulmonary immune functions and to pulmonary development and alveolar repair mechanisms following lung injury. AECI, together with the capillary endothelium, form the extremely thin barrier between alveolar air and blood. AECII produce and metabolize the surface-tension lowering and immune-modulating surfactant and are the progentiors of AECI. A great variety of processes rely on their normal functioning, including maintenance of the alveolar barrier; innate immune defense; and processes of differentiation, senescence, apoptosis, and autophagy. The wide range of AEC functions is nicely reflected by the diversity of topics addressed by the four review and eight original articles contained in this Special Issue of the International Journal of Molecular Sciences. Beyond the broad spectrum of topics, the authors of this issue also made use of an impressive variety of analytical methods, thus further illustrating the fascinating diversity of aspects related to AEC biology.

Kasper, Michael (editor)

Mühlfeld, Christian (editor)

https://directory.doabooks.org/handle/20.500.12854/69113

MDPI - Multidisciplinary Digital Publishing Institute

2020

Dewi Puspitasari

https://creativecommons.org/licenses/by/4.0/

Barkauskas, C.E.; Cronce, M.J.; Rackley, C.R.; Bowie, E.J.; Keene, D.R.; Stripp, B.R.; Randell, S.H.; Noble, P.W.;
Hogan, B.L. Type 2 alveolar cells are stem cells in adult lung. J. Clin. Investig 2013, 123, 3025–3036. [CrossRef]
[PubMed]

Pdf

English

Textbooks

DOI
10.3390/books978-3-03943-167-0

ISBN
9783039431663, 9783039431670

Basel